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Update 00_intro_to_variant_calling.md
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Gammerdinger authored Dec 13, 2023
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Expand Up @@ -66,12 +66,12 @@ Given the costs associated with whole genome sequencing (WGS) of each individual

**Exercise**

Use the figure below to try to make inferences answer the following questions:

<p align="center">
<img src="../img/Difficulty_of_assignment.png" width="400">
</p>

Use the figure above to try to make inferences answer the following questions:

**1.** If we assume there are no sequencing errors, are you more inclined to speculate that Locus 1 is a germline or somatic variant? Why?

**2.** Given the existence of sequencing errors, how confident are you that Locus 1 represents a heterozygous locus in the germline?
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