Brick | Description | Bricktools Status |
---|---|---|
1000_Genomes | The 1000 Genomes Project created a catalogue of common human genetic variation, using openly consented samples from people who declared themselves to be healthy. | |
bioportal | A comprehenisive repository of biomedical ontologies | |
chembl | A manually curated database of bioactive molecules with drug-like properties | |
clinvar | ClinVar aggregates information about genomic variation and its relationship to human health. | |
comptox | The CompTox Chemicals Dashboard is a part of a suite of databases and web applications developed by the US Environmental Protection Agency's Chemical Safety for Sustainability Research Program. These databases and apps support EPA's computational toxicology research efforts to develop innovative methods to change how chemicals are currently evaluated for potential health risks. EPA researchers integrate advances in biology, biotechnology, chemistry, and computer science to identify important biological processes that may be disrupted by the chemicals. The combined information helps prioritize chemicals based on potential health risks. Using computational toxicology research methods, thousands of chemicals can be evaluated for potential risk at small cost in a very short amount of time. | |
ctdbase | CTD is a robust, publicly available database that aims to advance understanding about how environmental exposures affect human health - http://ctdbase.org/ | |
ctgov | ClinicalTrials.gov is a database of privately and publicly funded clinical studies conducted around the world. | |
dbGaP | The database of Genotypes and Phenotypes (dbGaP) was developed to archive and distribute the data and results from studies that have investigated the interaction of genotype and phenotype in Humans. | |
dbSNP | The Single Nucleotide Polymorphism Database | |
depmap | The Cancer Dependency Map | |
fda | U.S. Food and Drug Administration database | |
gdc | The NCI's Genomic Data Commons (GDC) | |
gencode | Encyclopedia of genes and genes variants | |
GeneOntology | The Gene Ontology (GO) knowledgebase is the world’s largest source of information on the functions of genes | |
GTEx | The Genotype-Tissue Expression (GTEx) project is an ongoing effort to build a comprehensive public resource to study tissue-specific gene expression and regulation. | |
HGNC | The HGNC is a resource for approved human gene nomenclature containing ~42000 gene symbols and names and 1300+ gene families and sets | |
HPO | The Human Phenotype Ontology (HPO) provides a standardized vocabulary of phenotypic abnormalities encountered in human disease | |
ICE | ICE contains data sets curated for targeted toxicity endpoints by NICEATM, ICCVAM, and their partner organizations. ICE also contains other data sets that may be useful in evaluating or developing new approaches for assessing chemical safety. | |
LOINC | LOINC is a common language (set of identifiers, names, and codes) for identifying health measurements, observations, and documents. | |
meddra | a rich and highly specific standardised medical terminology to facilitate sharing of regulatory information internationally for medical products used by humans | |
MedGen | Organizes information related to human medical genetics, such as attributes of conditions with a genetic contribution. | |
miRBase | miRBase: the microRNA database | |
pharmgkb | The Pharmacogenomics Knowledge Base | |
pubmed | PubMed® comprises more than 34 million citations for biomedical literature | |
sider | SIDER contains information on marketed medicines and their recorded adverse drug reactions. | |
stringDB | STRING is a database of known and predicted protein-protein interactions. | |
TargetScan | TargetScan predicts biological targets of miRNAs by searching for the presence of conserved 8mer, 7mer, and 6mer sites that match the seed region of each miRNA | |
UMLS | The UMLS integrates and distributes key terminology, classification and coding standards, and associated resources to promote creation of more effective and interoperable biomedical information systems and services, including electronic health records. | |
uniprot | UniProt is a freely accessible database of protein sequence and functional information |
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