diff --git a/src/env.cc b/src/env.cc
index d907f65c27b892..36a1c1119dc8bd 100644
--- a/src/env.cc
+++ b/src/env.cc
@@ -540,6 +540,9 @@ void Environment::RegisterHandleCleanups() {
 }
 
 void Environment::CleanupHandles() {
+  Isolate::DisallowJavascriptExecutionScope disallow_js(isolate(),
+      Isolate::DisallowJavascriptExecutionScope::THROW_ON_FAILURE);
+
   for (ReqWrapBase* request : req_wrap_queue_)
     request->Cancel();
 
@@ -674,7 +677,7 @@ void Environment::RunAndClearNativeImmediates() {
 
       head->Call(this);
       if (UNLIKELY(try_catch.HasCaught())) {
-        if (!try_catch.HasTerminated())
+        if (!try_catch.HasTerminated() && can_call_into_js())
           errors::TriggerUncaughtException(isolate(), try_catch);
 
         // We are done with the current callback. Move one iteration along,
diff --git a/src/node_errors.cc b/src/node_errors.cc
index e094fe4681fc56..17c1bd7f55c0fb 100644
--- a/src/node_errors.cc
+++ b/src/node_errors.cc
@@ -278,6 +278,9 @@ static void ReportFatalException(Environment* env,
                                  Local<Value> error,
                                  Local<Message> message,
                                  EnhanceFatalException enhance_stack) {
+  if (!env->can_call_into_js())
+    enhance_stack = EnhanceFatalException::kDontEnhance;
+
   Isolate* isolate = env->isolate();
   CHECK(!error.IsEmpty());
   CHECK(!message.IsEmpty());
@@ -956,7 +959,7 @@ void TriggerUncaughtException(Isolate* isolate,
   }
 
   MaybeLocal<Value> handled;
-  {
+  if (env->can_call_into_js()) {
     // We do not expect the global uncaught exception itself to throw any more
     // exceptions. If it does, exit the current Node.js instance.
     errors::TryCatchScope try_catch(env,
diff --git a/src/node_process_events.cc b/src/node_process_events.cc
index 440e67d412322b..06096226625bb6 100644
--- a/src/node_process_events.cc
+++ b/src/node_process_events.cc
@@ -34,6 +34,8 @@ Maybe<bool> ProcessEmitWarningGeneric(Environment* env,
                                       const char* warning,
                                       const char* type,
                                       const char* code) {
+  if (!env->can_call_into_js()) return Just(false);
+
   HandleScope handle_scope(env->isolate());
   Context::Scope context_scope(env->context());