diff --git a/CHANGES.md b/CHANGES.md
index e9bbd5f99124..0932d8ed8c34 100644
--- a/CHANGES.md
+++ b/CHANGES.md
@@ -60,6 +60,7 @@
 
 * Support for X source added (Java/Python) ([#X](https://github.com/apache/beam/issues/X)).
 * Decreased TextSource CPU utilization by 2.3x (Java) ([#23193](https://github.com/apache/beam/issues/23193)).
+* Fixed bug when using SpannerIO with RuntimeValueProvider options (Java) ([#22146](https://github.com/apache/beam/issues/22146)).
 
 ## New Features / Improvements
 
diff --git a/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/BatchSpannerRead.java b/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/BatchSpannerRead.java
index f7715f9d9dc5..d1ac03b0b43a 100644
--- a/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/BatchSpannerRead.java
+++ b/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/BatchSpannerRead.java
@@ -17,6 +17,8 @@
  */
 package org.apache.beam.sdk.io.gcp.spanner;
 
+import static org.apache.beam.vendor.guava.v26_0_jre.com.google.common.base.Preconditions.checkNotNull;
+
 import com.google.auto.value.AutoValue;
 import com.google.cloud.spanner.BatchReadOnlyTransaction;
 import com.google.cloud.spanner.Options;
@@ -37,7 +39,6 @@
 import org.apache.beam.sdk.values.PCollection;
 import org.apache.beam.sdk.values.PCollectionView;
 import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.annotations.VisibleForTesting;
-import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.base.Preconditions;
 import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.cache.CacheBuilder;
 import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.cache.CacheLoader;
 import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.cache.LoadingCache;
@@ -118,8 +119,7 @@ public GeneratePartitionsFn(
         SpannerConfig config, PCollectionView<? extends Transaction> txView) {
       this.config = config;
       this.txView = txView;
-      Preconditions.checkNotNull(config.getRpcPriority());
-      Preconditions.checkNotNull(config.getRpcPriority().get());
+      checkNotNull(config.getRpcPriority());
     }
 
     @Setup
diff --git a/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/SpannerConfig.java b/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/SpannerConfig.java
index 2d3c15143c9a..05c8c8926d9c 100644
--- a/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/SpannerConfig.java
+++ b/sdks/java/io/google-cloud-platform/src/main/java/org/apache/beam/sdk/io/gcp/spanner/SpannerConfig.java
@@ -30,7 +30,6 @@
 import org.apache.beam.sdk.options.ValueProvider;
 import org.apache.beam.sdk.transforms.display.DisplayData;
 import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.annotations.VisibleForTesting;
-import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.base.Preconditions;
 import org.apache.beam.vendor.guava.v26_0_jre.com.google.common.collect.ImmutableSet;
 import org.checkerframework.checker.nullness.qual.Nullable;
 import org.joda.time.Duration;
@@ -161,8 +160,7 @@ public SpannerConfig withProjectId(String projectId) {
 
   /** Specifies the Cloud Spanner instance ID. */
   public SpannerConfig withInstanceId(ValueProvider<String> instanceId) {
-    Preconditions.checkNotNull(instanceId);
-    Preconditions.checkNotNull(instanceId.get());
+    checkNotNull(instanceId, "withInstanceId(instanceId) called with null input.");
     return toBuilder().setInstanceId(instanceId).build();
   }
 
@@ -173,8 +171,7 @@ public SpannerConfig withInstanceId(String instanceId) {
 
   /** Specifies the Cloud Spanner database ID. */
   public SpannerConfig withDatabaseId(ValueProvider<String> databaseId) {
-    Preconditions.checkNotNull(databaseId);
-    Preconditions.checkNotNull(databaseId.get());
+    checkNotNull(databaseId, "withDatabaseId(databaseId) called with null input.");
     return toBuilder().setDatabaseId(databaseId).build();
   }
 
@@ -185,8 +182,7 @@ public SpannerConfig withDatabaseId(String databaseId) {
 
   /** Specifies the Cloud Spanner host. */
   public SpannerConfig withHost(ValueProvider<String> host) {
-    Preconditions.checkNotNull(host);
-    Preconditions.checkNotNull(host.get());
+    checkNotNull(host, "withHost(host) called with null input.");
     return toBuilder().setHost(host).build();
   }
 
@@ -257,8 +253,7 @@ public SpannerConfig withRpcPriority(RpcPriority rpcPriority) {
 
   /** Specifies the RPC priority. */
   public SpannerConfig withRpcPriority(ValueProvider<RpcPriority> rpcPriority) {
-    Preconditions.checkNotNull(rpcPriority);
-    Preconditions.checkNotNull(rpcPriority.get());
+    checkNotNull(rpcPriority, "withRpcPriority(rpcPriority) called with null input.");
     return toBuilder().setRpcPriority(rpcPriority).build();
   }
 }